Balancing Complexity and Adherence: New AAD Guidelines for Managing Atopic Dermatitis
New guidelines from the American Academy of Dermatology (AAD) emphasize a range of topical treatments for managing atopic dermatitis (AD), including corticosteroids, calcineurin inhibitors, PDE-4 inhibitors, and JAK inhibitors.
Fish Collagen: A Promising Alternative for Atopic Dermatitis Treatment
Atopic dermatitis (AD) is a chronic inflammatory skin disorder marked by itching, redness, and barrier dysfunction, affecting a large global population. Current treatments, such as topical corticosteroids and immunosuppressants, provide temporary relief but carry risks with long-term use.
Adipokines and Atopic Dermatitis: Linking Obesity and Immune Dysregulation
Atopic dermatitis (AD) is a chronic skin condition marked by pruritus, inflammation, and xerosis, often linked with asthma and food allergies. Recent research reveals a significant connection between AD and obesity, with dysregulated adipokines—peptides from adipose tissue—playing a central role.
Atopic Dermatitis: Immune Dysregulation, Barrier Dysfunction, and Emerging Treatments
Atopic dermatitis (AD) is a complex inflammatory skin disorder influenced by immune dysregulation, barrier dysfunction, and pruritus. Key immune cells, including Th2 cells, ILC2s, and basophils, drive inflammation by releasing cytokines like IL-4, IL-5, IL-13, and IL-31, while alarmins such as TSLP, IL-25, and IL-33 amplify the response.
Hypoallergenic SPF 50 Sunscreen Proven Safe and Effective for Children With Atopic Dermatitis
Researchers of a recent study evaluated the safety and effectiveness of a hypoallergenic SPF 50 sunscreen (Anthelios Gentle Lotion Kids Sunscreen, L’Oréal) for children with atopic dermatitis (AD) or AD-prone skin.
Study Finds Severe Atopic Dermatitis Increases Glaucoma Surgery Risk
A recently published study found that patients with both glaucoma and severe atopic dermatitis (AD) are at a significantly higher risk of requiring glaucoma surgery compared with those without AD. Researchers in Taiwan reviewed data from the Global Collaborative Network in TriNetX, focusing on patients diagnosed with glaucoma between December 2003 and December 2018.
Understanding Itch: Complex Mechanism and Treatment Challenges in Atopic Dermatitis
Itch, or pruritus, is a complex sensation that triggers a desire to scratch, involving key organs like the skin, dorsal root ganglia, spinal cord, and brain. Itch signals are mainly transmitted by slower C-fiber sensory nerves, activated by external irritants and endogenous factors like cytokines. Chronic itch, especially in atopic dermatitis (AD), significantly affects quality of life and resists conventional treatments, emphasizing the need for improved understanding and management.
Experts: Recognizing Racial Variations in Atopic Dermatitis is Key to Improving Care
Physicians must recognize variations in atopic dermatitis (AD) presentation across different races, as highlighted by Dr. Melinda M. Rathkopf at the Annual Allergy, Asthma and Immunology CME Conference. AD is more prevalent and severe among Black, Hispanic, Asian, and Pacific Islander children, though treatment guidelines generally remain consistent. Diagnosing AD in darker skin can be challenging due to the subtler appearance of erythema. Social determinants of health, like access to care, further complicate diagnosis and treatment in minority populations.
New Guidelines for Managing Atopic Dermatitis With Topical Therapies
Updated evidence has emerged since the 2014 guidelines that further informs the management of atopic dermatitis (AD) with topical therapies. These updated guidelines provide evidence-based recommendations for managing AD in adults using a variety of topical treatments. A multidisciplinary workgroup conducted a systematic review and used the GRADE approach to assess the certainty of evidence and to formulate and grade recommendations.
Study Reveals Patients With Atopic Dermatitis Prioritize Itch Control and Reducing Adverse Events
Researchers of a study revealed that patients with atopic dermatitis (AD) prioritize treatments that effectively control itch while minimizing adverse event risks. The study highlighted various treatment options for moderate-to-severe AD, including systemic therapies, biologics, and newer options like Janus kinase inhibitors and monoclonal antibodies.
