Unpacking the Complexities of Severe Eczema: Infections, Allergies, Asthma, and More

A medically-reviewed article from WebMD analyzed the complications of severe eczema. Beyond itchy skin, severe eczema brings risks of infections, allergies, and asthma, as well as sleepless nights, fatigue, and even depression. Adults face isolation, eye problems, and job disruptions due to the condition. Long-term health concerns like heart disease may be linked, though research continues.

Prolonged Corticosteroid Treatment in Atopic Dermatitis Raises Concerns

Researchers of a study found that prolonged corticosteroid treatment for atopic dermatitis (AD) had negative effects on both adults and children. While topical corticosteroids (TCS) are commonly used for AD, their prolonged use can lead to issues like topical steroid withdrawal syndrome. Researchers of the study, involving 2,160 participants, raised concerns about TCS cumulative effects, including worsened symptoms and adverse events.

Video Commentary Explores Pollution-Atopic Dermatitis Connection and Tapinarof Treatment Potential

In a video commentary, Karan Lal, DO, MS, explores the link between environmental pollutants and atopic dermatitis (AD) flares, focusing on the AhR pathway’s role in inflammation and itch caused by pollutants. Tapinarof cream, which targets AhR, holds potential for AD treatment, particularly in polluted urban areas. Dr. Lal stresses the need to educate patients about the effects of factors like smoking on AD, as they can activate the AhR pathway, potentially exacerbating the condition.