Research shows that the skin microbiome, crucial in interacting with the host, is disrupted in atopic dermatitis (AD) by an excess of S. aureus and less diversity. Early life emerges as a key period for shaping immune responses, indicating a potential window for AD microbiome interventions. Current studies on the microbial differences between healthy and AD skin have spurred clinical trials of biotherapeutics to address AD microbiome dysbiosis, indicating potential in microbiome-based treatments.

Reference: Koh LF, Ong RY, Common JE. Skin microbiome of atopic dermatitis. Allergol Int. 2022;71(1):31-39. doi:10.1016/j.alit.2021.11.001