Authors of a review examined infectious complications in atopic dermatitis (AD). Key contributing factors identified include skin barrier defects, type 2 inflammation, Staphylococcus aureus colonization, and cutaneous dysbiosis. Prevention strategies for AD-related infections prioritize skin barrier enhancement and anti-inflammatory treatments. Additional research is required to establish the appropriate use of antibiotics in AD exacerbations, given the significant comorbidity of infectious complications.

Reference: Wang V, Boguniewicz J, Boguniewicz M, Ong PY. The infectious complications of atopic dermatitis. Ann Allergy Asthma Immunol. 2021;126(1):3-12. doi:10.1016/j.anai.2020.08.002