Study Identifies Skin Microbe Link to Eczema Itching: Potential for New Treatments

Eczema affects millions globally, with itch being a prominent symptom that impacts quality of life. Recent research investigated a potential link between eczema and oral microbiota, finding poorer oral health and altered microbial diversity in patients with eczema compared with controls. This highlights the need for increased awareness and potential therapeutic interventions for oral health issues in those with eczema.

Meanwhile, a separate study explored the role of a specific skin microbe, Staphylococcus aureus, in driving itch associated with eczema. Through animal models and human tissue analysis, researchers identified a bacterial enzyme, protease V8, as a key trigger for itch response by interacting with a specific receptor. This discovery opens doors for potential topical treatments targeting this enzyme to alleviate eczema itching, though further research is needed to develop effective therapies.

Reference: Newman T. How eczema research on skin bacteria may lead to a treatment for itching. Medical News Today. Published March 8, 2024. Accessed April24, 2024. https://www.medicalnewstoday.com/articles/how-eczema-research-on-skin-bacteria-may-lead-to-a-treatment-for-itching

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